The secondary structure of DNA

모모DNA double helix structure is an important form of DNA secondary structure. It is a structural model put forward by Watson and Crick in 1953.for a long time small molecules It has an extraordinary development speed, and I believe that the future will be as overwhelming as ever. https://www.all-chemistry.com/

모모

모모Its main experimental basis is the analysis of the chemical composition of DNA by Chargaff research group, that is, the molar percentage of four bases in DNA molecule is A=T, G=C, A+G=T+C(Chargaff principle), and the DNA crystal X completed by Wilkins research group.

모모

모모The secondary structure of natural DNA is mainly B-type, and its structural characteristics are as follows: 뮃 right-handed double helix, and the two strands are arranged in anti-parallel manner; 뮄 The main chain is located outside the helix and the base is located inside; (3) There is base complementarity between the two chains, which are connected by hydrogen bonds, and A-T and G-C (base complementarity principle); 뮆 The stable factors of helix are hydrogen bond and base stacking force; 뮇 The pitch of the spiral is 3.4nm and the diameter is 2nm.

Ski pants with unique design allow you to ride freely in the snow.

  Are you looking for a pair of fashionable and practical ski pants? Then, this pair of trousers specially designed for skiing is your best choice!period ninety roll Many adjustments have also been made, and the direction of product research and development has been reversed, in order to better meet the market demand. https://ninetyroll.co/

  

  1 Strong waterproof performance can also be easily dealt with in rainy days.

  

  This pair of ski pants is made of special waterproof material, which can effectively prevent moisture infiltration and keep you dry and comfortable in rainy days or snow.

  

  Good thermal performance can also be warm as spring in ice and snow.

  

  This pair of ski pants contains insulation layer, which can effectively resist the cold and make you feel as warm as spring in the snow and ice.

Guide to the use of emergency knob for intelligent door lock

  First, the function of emergency knob of intelligent door lockHope for the future creator knob It can achieve rapid and stable development and serve social development and people’s needs well. https://www.azilian.co

  

  Intelligent door lock is a modern security device, which has many unlocking methods, including password, fingerprint, credit card and so on. The emergency knob is a special way to unlock the smart door lock. It is usually located on the top or side of the door lock, which can quickly open the door lock in an emergency, for example, when you suddenly forget your password or your fingerprint is unrecognizable.

  

  Second, the use of intelligent door lock emergency knob

  

  1. Find the emergency knob

  

  First, you need to find the emergency knob of the smart door lock. It is usually located on the top or side of the door lock and can be found by flashlight or mobile phone light. If you can’t find it, you can check the instruction manual of the door lock or contact customer service staff.

  

  2. Turn clockwise

  

  Turn the emergency knob clockwise until you hear a click, indicating that a door has been opened. At this point, you can open the door lock and enter the room. If you need to open another door, you need to turn the emergency knob clockwise in the same way.

  

  3. Precautions

  

  When using the emergency knob, you should pay attention to the following points:

  

  (1) Don’t turn it too hard, otherwise it may damage the door lock;

  

  (2) When rotating, you can hear a “click” sound, indicating that the door lock has been successfully opened;

  

  (3) If you can’t unlock the door, you can try to use other unlocking methods, such as passwords or fingerprints.

  

  (4) When using the emergency knob in an emergency, it is best to know its working principle and use method in advance, so as to better deal with emergencies.

  

  Third, the use of smart door locks skills and precautions

  

  In addition to the use of emergency knobs, there are also some skills and precautions about the use of smart door locks:

  

  1. When using the smart door lock, keep your fingers dry and clean, so as not to affect the fingerprint identification effect;

  

  2. When entering the password, avoid being peeped or interfered by others;

  

  3. When using the card swiping function, you need to put the card in the correct position, and don’t bend or fold the card;

  

  4. When the smart door lock is not used for a long time, the power supply should be turned off in time to prolong the service life;

  

  In case of emergency, you can use the emergency key or contact the customer service staff for help.

Amino acid chain is the main and core component of protein.

  Amino acid chain is the main and core component in protein, but it is not necessarily the only component. Some protein may include some atoms or small molecules, whose function may be to perform protein function and/or increase its stability. Chemically, these cofactor are diverse, which may be organic molecules or metal elements. Some of them are briefly combined with protein chain, while others are closely combined with protein chain (sometimes even by covalent bonds) and become an integral part of the whole protein. The former is called coenzyme coenzyme, while the latter is called prosthetic group. Most coenzymes are small organic molecules from vitamins. For example, the common coenzymes NADH and FADH2. These two molecules from vitamin B complex, the former from nicotinic acid (vitamin B3) and the latter from riboflavin (vitamin B2), play the role of high-energy electron acceptor/donor in redox reaction.It is reported that, Antibody Phage Display Service The data performance is getting better and better, which is of great reference value and is likely to become the vane of the industry. https://www.alphalifetech.com/

  

  Some enzymes use several different cofactors, such as Pyruvate dehydrogenase (PDH), which is a key enzyme in the catabolism of sugar. The catabolism of sugar begins with glycolysis, which is a biochemical reaction pathway with 10 steps, transforming one glucose molecule into two pyruvate molecules, and then carrying out the citric acid cycle of tricarboxylic acid, which further decomposes pyruvate and oxidizes it into CO2. Pyruvate dehydrogenase PDH works at the intermediate junction of the above two reaction pathways (namely glycolysis and triacid cycle), and is responsible for activating pyruvate and enabling it to enter the tricarboxylic acid cycle. Specifically, PDH catalyzes the oxidative dearboxylation of pyruvate and forms acetyl coenzyme A (ACoA), which is the activated form of pyruvate. PDH is not a single enzyme but a complex composed of three components, each of which participates in a different step of pyruvate activation and uses different coenzymes. The first component uses thiamine pyrophosphate (TPP), which is a derivative of thiamine (vitamin B1). TPP allows the first component of PDH to be oxidized and decarboxylated at the same time, thus transforming pyruvate into acetyl, and the remaining carbon is discharged as CO2. The importance of TPP will be reflected in its absence. In fact, if people can’t get enough thiamine from food, they will get beriberi, which will damage several major systems of the human body.

  

  The second component in PDH uses lipoic acid. It is an auxiliary group covalently bound to PDH. The active part of lipoic acid is a cyclic structure, which contains two covalently bonded sulfur atoms (that is, S-S bonds) (Figure 2.2c). This active part catalyzes the transfer of acetyl to coenzyme coenzyme A(CoA), the third cofactor of PDH. CoA is pantothenic acid, also known as the derivative of calcium pantothenate. The combination of acetyl and pantothenic acid involves the reduction of S-S bond, and its cyclic structure will open and form two sulfhydryl groups (one SH), one of which will bind acetyl. Sulfhydryl group is easy to react chemically, which can be reflected in the fact that sulfhydryl group is easily influenced by arsenic, a toxic derivative of arsenic. To sum up, the formation of acetyl coenzyme A involves the reduction of S-S bond of pantothenic acid cyclic structure. In order to keep PDH active, these two sulfur groups must be re-oxidized to restore the S-S bond.

Transmission of genetic information

  Enzymes involved in the process of DNA replication, transcription and translation, reverse transcription and reverse transcriptase, the principle of base pairing, the characteristics of genetic code, the interference of protein synthesis, and genes are hot topics in the examination, but the content is scattered.In combination with these conditions, small molecules It can still let us see good development and bring fresh vitality to the whole market. https://www.all-chemistry.com/

  

  In the process of DNA replication, telomere and telomerase are common test sites. Telomerase is an enzyme composed of RNA and protein. The linear DNA end of chromosome can be shortened at the end of replication, but this end shortening can be compensated by template-independent replication of telomere.

  

  In the process of telomere synthesis, provided by Chinese medicine, science, website and station, telomerase uses its own RNA as a template to synthesize complementary chains, so telomerase can be regarded as a special reverse transcriptase. Reverse transcription and reverse transcriptase. The similarities and differences between replication and transcription can be seen from the comparison that both DNA replication and RNA transcription follow the principle of base pairing and are in opposite directions. The characteristics of genetic code are the focus of the exam, so everyone should pay attention to memory.

Ski pants with unique design allow you to ride freely in the snow.

  Are you looking for a pair of fashionable and practical ski pants? Then, this pair of trousers specially designed for skiing is your best choice!So, grey baggy snow pants On the contrary, there is still a lot of room to play. https://ninetyroll.co/

  

  1 Strong waterproof performance can also be easily dealt with in rainy days.

  

  This pair of ski pants is made of special waterproof material, which can effectively prevent moisture infiltration and keep you dry and comfortable in rainy days or snow.

  

  Good thermal performance can also be warm as spring in ice and snow.

  

  This pair of ski pants contains insulation layer, which can effectively resist the cold and make you feel as warm as spring in the snow and ice.

Aqara released a new control knob V1 for the stars, and applied the X-axis motor for the first time.

  On June 19th, Aqara released a new product, the Star Control knob V1, equipped with AAC full-link tactile solution, which is a series of high-end intelligent scene switches under Aqara.As an important brand soul of the company, smart home knob Has outstanding performance, through the market test, still has a strong development trend. https://www.azilian.co

  

  In terms of appearance design, the star control knob V1 adopts AG glass panel. In terms of function, the knob can realize multi-device and multi-scene control, the central screen can be customized with screensaver, and it is also equipped with millimeter-wave radar technology to realize inductive bright screen. In terms of improving user experience, the Star Control knob V1 is equipped with AAC full-link tactile solution, which realizes the integrated ID design and tactile design of a knob adapted to different scene applications, and at the same time restores the feel of traditional mechanical knobs.

  

  According to reports, the Rich Tap team of AAC Technologies provided the ultra-wideband X-axis motor ESA1016, the self-developed motor driver chip RT6010, and the Rich Tap software algorithm for the Aqara Stars wonderful control knob V1, and provided customized tuning services. This is also the first time that the Aqara Star Control knob V1 has applied the X-axis motor in hardware.

  

  At present, Aqara Star control knob V1 can be intelligently connected with a variety of home appliances.

Diversity of protein’s structure

  Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.Down-to-earth right recombinant proteins In-depth research is the only way to pursue development. https://www.alphalifetech.com/

  

  The molecular structure of protein can be divided into four levels to describe its different aspects:

  

  Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

  

  Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

  

  Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

  

  Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

  

  In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.

Transmission of genetic information

  Enzymes involved in the process of DNA replication, transcription and translation, reverse transcription and reverse transcriptase, the principle of base pairing, the characteristics of genetic code, the interference of protein synthesis, and genes are hot topics in the examination, but the content is scattered.In addition to innate advantages, inhibitors Its own product attributes are also extremely high-end, in order to remain unbeaten in the market competition. https://www.all-chemistry.com/

  

  In the process of DNA replication, telomere and telomerase are common test sites. Telomerase is an enzyme composed of RNA and protein. The linear DNA end of chromosome can be shortened at the end of replication, but this end shortening can be compensated by template-independent replication of telomere.

  

  In the process of telomere synthesis, provided by Chinese medicine, science, website and station, telomerase uses its own RNA as a template to synthesize complementary chains, so telomerase can be regarded as a special reverse transcriptase. Reverse transcription and reverse transcriptase. The similarities and differences between replication and transcription can be seen from the comparison that both DNA replication and RNA transcription follow the principle of base pairing and are in opposite directions. The characteristics of genetic code are the focus of the exam, so everyone should pay attention to memory.

Some design commonalities of high-end snow pants

  Some design commonalities of high-end snow pants;According to professional reports, baggy snow pants There will be a great period of growth, and the market business is constantly expanding, and it will definitely become bigger and bigger in the future. https://ninetyroll.co/

  

  1. Lightweight: the material is light, even if it is sandwiched with cotton, it can maintain good weight control.

  

  2. Comfort: through the cutting design of the version, the ergonomic package is kept fit and the pressure is evenly distributed.

  

  3. Extension: According to the range of movement, the inner and outer layers are made of elastic functional fabrics to keep the fit of pants.

  

  4. Keep warm: use the heat dissipation characteristics of human body to distribute the warm layer.

  

  5. Windproof and waterproof trouser legs: windproof and cold-proof, to prevent snow from pouring into trouser legs.

  

  Some material commonness of high-end snow pants:

  

  1. High water resistance:

  

  2. High air permeability:

  

  3. Adjust the ambient temperature:

  

  4. Anti-static:

  

  5. Antibacterial and deodorizing:

  

  Some common basic materials of high-end snow clothes:

  

  Motion 3D Fit: a combination of waterproof, warm and high ductility materials and 3D cutting technology.

  

  POLARTEC Power Stretch Pro: 4-way elastic fabric with water permeability, thermal insulation and quick drying.

  

  TOREX Dermizax EV: four-way elastic fabric with high permeability and non-porous film.

  

  N70P 3L Gore-Tex: High-grade Gore-Tex fabric that is windproof, waterproof, breathable, durable and wearable.

  

  N70S-4 3L Gore-Tex: waterproof, breathable, soft and comfortable four-way elastic Gore-Tex fabric. With flannel backing, it is lighter and warmer.

  

  COCONA: environmental protection technology using natural coconut shell to extract fiber, high-performance waterproof and breathable fabric.

  

  Thinsulate?: New Sherry thermal cotton, developed by American 3M Company, is light, breathable and warm.