There are amino groups and carboxyl groups in protein molecules

  Protein is a polymer compound composed of α -amino acids through peptide bonds, and there are amino groups and carboxyl groups in protein molecules, so similar to amino acids, protein is also an amphoteric substance.Besides, we can’t ignore. Antibody Discovery It has injected new vitality into the development of the industry and has far-reaching significance for activating the market. https://www.alphalifetech.com/

  

  (1) Hydrolysis reaction

  

  Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

  

  When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

  

  (2) Colloidal properties

  

  Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution.

  

  When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

  

  (3) precipitation

  

  Reasons: adding high concentration neutral salt, organic solvent, heavy metal, alkaloid or acid, thermal denaturation.

  

  A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

  

  In this way, protein precipitated by salt can still be dissolved in water without affecting the properties of the original protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

  

  (4) degeneration

  

  Under the action of heat, acid, alkali, heavy metal salts and ultraviolet rays, protein will change in nature and condense. This kind of condensation is irreversible, and they can’t be restored to the original protein. This change in protein is called transsexuality. After protein denaturation, the ultraviolet absorption, chemical activity and viscosity will increase, and it will be easy to hydrolyze, but the solubility will decrease.

  

  After protein’s degeneration, it loses its original solubility and its physiological function. Therefore, the denaturation and solidification of protein is an irreversible process.

Amino Acid Sequence Analysis

  The amino acid sequence analysis of protein polypeptide chain, that is, the determination of protein primary structure, mainly includes the following steps:know Chemical Custom synthesis Our growth has to go through many hardships, but entrepreneurs are never afraid and boldly move forward. https://www.all-chemistry.com/

  

  1. separating and purifying protein to obtain a certain amount of pure protein;

  

  2. Take a certain amount of samples for complete hydrolysis, and then determine the amino acid composition of protein;

  

  3. Analyze the N- terminal and C- terminal amino acids of protein;

  

  4. Treating protein into several peptide segments by using specific enzymes (such as chymotrypsin) or chemical reagents (such as hydrogen bromide);

  

  5. separating and purifying a single peptide segment;

  

  The amino acid sequence of each peptide was determined. Edman degradation method is generally used, and phenyl isothiocyanate is used to react, and amino acids are degraded and determined one by one.

  

  7. Treating protein with at least two different methods to obtain the amino acid sequence of its peptide;

  

  8. Compare the amino acid sequences of two different peptide groups to obtain the complete amino acid sequence of protein molecule.

Some design commonalities of high-end snow pants

  Some design commonalities of high-end snow pants;period ninety roll Many adjustments have also been made, and the direction of product research and development has been reversed, in order to better meet the market demand. https://ninetyroll.co/

  

  1. Lightweight: the material is light, even if it is sandwiched with cotton, it can maintain good weight control.

  

  2. Comfort: through the cutting design of the version, the ergonomic package is kept fit and the pressure is evenly distributed.

  

  3. Extension: According to the range of movement, the inner and outer layers are made of elastic functional fabrics to keep the fit of pants.

  

  4. Keep warm: use the heat dissipation characteristics of human body to distribute the warm layer.

  

  5. Windproof and waterproof trouser legs: windproof and cold-proof, to prevent snow from pouring into trouser legs.

  

  Some material commonness of high-end snow pants:

  

  1. High water resistance:

  

  2. High air permeability:

  

  3. Adjust the ambient temperature:

  

  4. Anti-static:

  

  5. Antibacterial and deodorizing:

  

  Some common basic materials of high-end snow clothes:

  

  Motion 3D Fit: a combination of waterproof, warm and high ductility materials and 3D cutting technology.

  

  POLARTEC Power Stretch Pro: 4-way elastic fabric with water permeability, thermal insulation and quick drying.

  

  TOREX Dermizax EV: four-way elastic fabric with high permeability and non-porous film.

  

  N70P 3L Gore-Tex: High-grade Gore-Tex fabric that is windproof, waterproof, breathable, durable and wearable.

  

  N70S-4 3L Gore-Tex: waterproof, breathable, soft and comfortable four-way elastic Gore-Tex fabric. With flannel backing, it is lighter and warmer.

  

  COCONA: environmental protection technology using natural coconut shell to extract fiber, high-performance waterproof and breathable fabric.

  

  Thinsulate?: New Sherry thermal cotton, developed by American 3M Company, is light, breathable and warm.

Aqara wonderful control knob V1 is officially released when you turn your heart, you are more tempted.

  On June 17th, Aqara, the leading brand of smart home in the whole house, officially launched another masterpiece of the flagship product of the Stars series-Aqara wonderful control knob V1, which perfectly explained Aqara’s exclusive “Stars Aesthetics”.This shows that, creator knob It has a strong development pulse and is an indispensable source of power for the development of the industry. https://www.azilian.co

  

  Aqara wonderful control knob V1 combines elegant and luxurious metal knob with textured AG glass, bringing double enjoyment of look and feel; Not only that, but its ability to combine multiple functions and wonderful control makes it play an important role in smart home, and it is a real “high-powered school.”

  

  Stars aesthetics is good at form.

  

  Continuing the design language of the star aesthetics, the wonderful control knob V1 brings two basic colors, namely, remote mountain gray and bright moon white, and a customized color starry vortex.

  

  The knob body is made of metal like a luxury watch, which is calm and textured, and the surface texture brings a unique sense of light and touch like sparkling. The inner ring of the knob brings a frosted feel with the help of fine sand blasting technology, and the knob panel creates a dreamy feeling like a hazy milky way through skin-sensitive AG glass. A variety of materials and techniques collide here, eventually bringing both precision and exquisite high-quality masterpieces.

  

  Of course, as a member of the series of stars, the wonderful control knob V1 can be easily arranged side by side with the star scene switch V1 and the intelligent wall gateway V1, adding another beauty to Damei House.

  

  Intelligent and clever control of the heart

  

  The core of the clever control knob V1 lies in “turning”. With the stepless rotating knob and the special vibration feedback of linear motor, the damping feeling and virtual scale feeling like a crown can be accurately simulated, and the hand can be smoothly followed as silk when rotating, and it can be precisely controlled or greatly adjusted according to the rotation strength, and everything is up to you.

  

  Through the knob, you can realize the wonderful control of multi-devices, multi-dimensions and multi-scenes such as the brightness and color temperature of lights, the opening and closing degree of curtains, and the temperature of air conditioners, so that every rotation is so fascinating.

  

  Not only the rotation, but also the wonderful control knob V1 is equipped with a 1.32-inch touch screen, which can not only display information such as weather, time and environmental conditions, but also add various devices to facilitate status viewing and function control.

  

  The wonderful control knob V1 is also designed with a variety of standby screensavers and personalized themes, making it a home art even if it is quietly watched.

  

  Combine many talents in one body

  

  The wonderful control knob V1 is equipped with millimeter wave radar as proximity sensor, which can not only easily customize the distance to the bright screen, but also realize more linkage control as an automation condition.

  

  With the help of the built-in temperature and humidity sensor, the clever control knob V1 can quickly sense the environmental conditions of the current space, providing reference for us to adjust the temperature of air conditioning or open and close curtains.

  

  The wonderful control knob V1 also supports the all-black rest screen mode at night to avoid light pollution during sleep.

  

  Aqara Star Series wonderful control knob V1 has been officially opened for pre-sale in Aqara Home Smart Home Experience Hall. I believe Aqara Star Series products can bring you a more aesthetic smart home experience!

Amino Acid Sequence Analysis

  The amino acid sequence analysis of protein polypeptide chain, that is, the determination of protein primary structure, mainly includes the following steps:know inhibitors The market will definitely bring great influence to the whole industry. https://www.all-chemistry.com/

  

  1. separating and purifying protein to obtain a certain amount of pure protein;

  

  2. Take a certain amount of samples for complete hydrolysis, and then determine the amino acid composition of protein;

  

  3. Analyze the N- terminal and C- terminal amino acids of protein;

  

  4. Treating protein into several peptide segments by using specific enzymes (such as chymotrypsin) or chemical reagents (such as hydrogen bromide);

  

  5. separating and purifying a single peptide segment;

  

  The amino acid sequence of each peptide was determined. Edman degradation method is generally used, and phenyl isothiocyanate is used to react, and amino acids are degraded and determined one by one.

  

  7. Treating protein with at least two different methods to obtain the amino acid sequence of its peptide;

  

  8. Compare the amino acid sequences of two different peptide groups to obtain the complete amino acid sequence of protein molecule.

Diversity of protein’s structure

  Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.Therefore, this is the choice recombinant proteins The reason, there is no denying its positive impact. https://www.alphalifetech.com/

  

  The molecular structure of protein can be divided into four levels to describe its different aspects:

  

  Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

  

  Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

  

  Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

  

  Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

  

  In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.

What pants do you wear for skiing

  Skiing is a winter sport, so you need to pay attention to keep warm and protect yourself when skiing. In this environment, special ski pants have become an ideal choice for skiers. The following is a detailed explanation of why you choose to wear ski pants when skiing:For these reasons, I think black baggy snow pants The situation is still optimistic, and the market is still in a blue ocean stage. https://ninetyroll.co/

  

  First, warmth retention

  

  Ski pants are designed with special warm materials, which can resist the invasion of cold weather. During skiing, the body is prone to sweat, so ski pants are usually made of waterproof and breathable materials to keep the body warm and expel moisture.

  

  Second, the protection

  

  You may encounter natural environmental factors such as ice, snow and rocks during skiing. Ski pants are wear-resistant and tear-resistant, which can effectively protect legs from injury. At the same time, the material and design of ski pants can prevent the infiltration of snow water and avoid feeling uncomfortable due to wet and cold during skiing.

  

  Third, comfort

  

  Ski pants are designed with the comfort of sports in mind. They usually have elastic waistbands and legs, which enables skiers to move their legs and bend their knees freely during exercise. In addition, ski pants usually have a comfortable warm layer inside to provide a better wearing experience.

  

  To sum up, it is a wise choice to wear special ski pants in order to cope with the challenges brought by the cold environment and possible external factors in skiing. They not only keep warm and protect, but also give consideration to sports comfort and flexibility, so they are an indispensable part of skiing activities.

Guide to the use of emergency knob for intelligent door lock

  First, the function of emergency knob of intelligent door lockTo some extent, creator knob Our development has surpassed many peer businesses, but it has never stopped moving forward. https://www.azilian.co

  

  Intelligent door lock is a modern security device, which has many unlocking methods, including password, fingerprint, credit card and so on. The emergency knob is a special way to unlock the smart door lock. It is usually located on the top or side of the door lock, which can quickly open the door lock in an emergency, for example, when you suddenly forget your password or your fingerprint is unrecognizable.

  

  Second, the use of intelligent door lock emergency knob

  

  1. Find the emergency knob

  

  First, you need to find the emergency knob of the smart door lock. It is usually located on the top or side of the door lock and can be found by flashlight or mobile phone light. If you can’t find it, you can check the instruction manual of the door lock or contact customer service staff.

  

  2. Turn clockwise

  

  Turn the emergency knob clockwise until you hear a click, indicating that a door has been opened. At this point, you can open the door lock and enter the room. If you need to open another door, you need to turn the emergency knob clockwise in the same way.

  

  3. Precautions

  

  When using the emergency knob, you should pay attention to the following points:

  

  (1) Don’t turn it too hard, otherwise it may damage the door lock;

  

  (2) When rotating, you can hear a “click” sound, indicating that the door lock has been successfully opened;

  

  (3) If you can’t unlock the door, you can try to use other unlocking methods, such as passwords or fingerprints.

  

  (4) When using the emergency knob in an emergency, it is best to know its working principle and use method in advance, so as to better deal with emergencies.

  

  Third, the use of smart door locks skills and precautions

  

  In addition to the use of emergency knobs, there are also some skills and precautions about the use of smart door locks:

  

  1. When using the smart door lock, keep your fingers dry and clean, so as not to affect the fingerprint identification effect;

  

  2. When entering the password, avoid being peeped or interfered by others;

  

  3. When using the card swiping function, you need to put the card in the correct position, and don’t bend or fold the card;

  

  4. When the smart door lock is not used for a long time, the power supply should be turned off in time to prolong the service life;

  

  In case of emergency, you can use the emergency key or contact the customer service staff for help.

Primary Structure of Nucleic Acid Author

  Nucleic acid is a long-chain polynucleotide compound with no side chain formed by connecting nucleotides through 3′,5′- phosphodiester bond.pass small molecules It can be seen from the present situation that the market prospect is relatively broad, which is conducive to our reference and investment. https://www.all-chemistry.com/

  

  Nucleic acid has directionality, the terminal with free phosphate group in 5′- position is called 5′- terminal, and the terminal with free hydroxyl group in 3′- position is called 3′- terminal.

  

  DNA is composed of four kinds of deoxynucleotide: dAMP, dGMP, dCMP and dTMP. Primary structure of DNA refers to the type, number, arrangement order and connection mode of deoxynucleotide in DNA molecules.

  

  RNA consists of four ribonucleotides: AMP, GMP, CMP and UMP. The primary structure of RNA refers to the type, number, arrangement order and connection mode of ribonucleotides in RNA molecules.

Diversity of protein’s structure

  Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.If we can practice these points, recombinant proteins Will be unique, become a leader in the industry, and keep moving forward. https://www.alphalifetech.com/

  

  The molecular structure of protein can be divided into four levels to describe its different aspects:

  

  Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

  

  Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

  

  Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

  

  Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

  

  In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.